Dental restorative materials with high mechanical properties and biocompatible performances are promising. In this work, polymer-infiltrated-ceramic-network materials (PICNs) were fabricated via infiltrating polymerizable monomers into porous ceramic networks and incorporated with hydroxyapatite nano-powders. Our results revealed that the flexural strength can be enhanced up to 157.32 MPa, and elastic modulus and Vickers hardness can be achieved up to 19.4 and 1.31 GPa, respectively, which are comparable with the commercial computer-aided design and computer-aided manufacturing (CAD/CAM) blocks. Additionally, the adhesion and spreading of rat bone marrow mesenchymal stem cells (rBMSCs) on the surface of such materials can be improved by adding hydroxyapatite, which results in good biocompatibility. Such PICNs are potential applicants for their application in the dental restoration.

中文翻译：

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聚合物渗透性陶瓷网络材料在牙齿修复中的力学和生物相容性

具有高机械性能和生物相容性的牙科修复材料是有前途的。在这项工作中，通过将可聚合单体渗透到多孔陶瓷网络中并掺入羟基磷灰石纳米粉体来制造聚合物浸渗陶瓷网络材料（PICN）。我们的结果表明，弯曲强度可以提高到157.32 MPa，弹性模量和维氏硬度分别可以达到19.4和1.31 GPa，这与商业计算机辅助设计和计算机辅助制造（CAD）相当/ CAM）块。另外，通过添加羟基磷灰石可以改善大鼠骨髓间充质干细胞（rBMSC）在此类材料表面上的粘附和扩散，从而产生良好的生物相容性。