Methanol as a chemical feedstock is becoming increasingly important as it is derived from natural gas and is a feasible end‐product for captured carbon dioxide. Biological conversion of methanol through natural and synthetic methylotrophs increases the chemical repertoire and is an important direction for one carbon (C1) based chemical economy. Advances in the metabolic engineering and synthetic biology enable development of microbial cell factories for converting methanol into various platform chemicals. In this review, the current status of methanol utilizing microbial factory development is summarized. Also the development of synthetic methylotrophy and methanol‐augmented bioproductions is discussed.

中文翻译：

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使用天然和合成的甲基营养生物从甲醇化学生产。

甲醇作为化学原料越来越重要，因为它来自天然气，是捕获二氧化碳的可行的最终产品。甲醇通过天然和合成甲基营养生物的转化增加了化学组成，并且是基于一种碳（C1）的化学经济的重要方向。代谢工程学和合成生物学的进步推动了微生物细胞工厂的发展，这些工厂将甲醇转化为各种平台化学品。在这篇综述中，总结了利用微生物工厂发展的甲醇的现状。还讨论了合成甲基营养素和甲醇增强生物制品的开发。