The antidiabetic properties of Tiliacora triandra ethanol extract in diabetic rats induced with high‐fat diet (HFD)/streptozotocin (STZ) was investigated. Rats were fed with HFD for 4 weeks to induced insulin resistance, and thereafter administered with 35 mg/kg of STZ to induce diabetes. Diabetic rats received 100 and 400 mg/kg of T. triandra daily for 30 days. The body weight, blood glucose level, food and fluid intake were monitored. Furthermore, biochemical and histological assessment was performed to evaluate the hypoglycemic effect of the extract in the treated rats. T. triandra significantly decreased the blood glucose level, increased the body weight and insulin secretion. Furthermore, T. triandra attenuated hyperlipidemia, improved liver and kidney functions of treated diabetic rats. Thus, T. triandra could effectively attenuate diabetes and it complications.

中文翻译：

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ilia藜提取物在高脂饮食/链脲佐菌素诱导的大鼠糖尿病中具有抗糖尿病作用。

研究了高脂饮食（HFD）/链脲佐菌素（STZ）诱导的T虫乙醇提取物对糖尿病大鼠的抗糖尿病作用。给大鼠喂食HFD 4周以诱导胰岛素抵抗，然后给予35 mg / kg的STZ诱导糖尿病。糖尿病大鼠每天接受100和400 mg / kg的山毛榉木，持续30天。监测体重，血糖水平，食物和液体摄入量。此外，进行了生化和组织学评估以评估提取物在治疗大鼠中的降血糖作用。T. triandra显着降低了血糖水平，增加了体重和胰岛素分泌。此外，T。triandra减轻高脂血症，改善糖尿病大鼠的肝肾功能。因此，T。triandra可以有效减轻糖尿病及其并发症。