Microbeam radiation therapy (MRT) utilizes highly collimated synchrotron generated x-rays to create narrow planes of high dose radiation for the treatment of tumors. Individual microbeams have a typical width of 30–50 µm and are separated by a distance of 200–500 µm. The dose delivered at the center of the beam is lethal to cells in the microbeam path, on the order of hundreds of Grays (Gy). The tissue between each microbeam is spared and helps aid in the repair of adjacent damaged tissue. Radiation interactions within the peak of the microbeam, such as the photoelectric effect and incoherent (atomic Compton) scattering, cause some dose to be delivered to the valley areas adjacent to the microbeams. As the incident x-ray energy is modified, radiation interactions within a material change and affect the probability of interactions, as well as the directionality and energy of ionizing particles (electrons) that deposit energy in the valley regions surrounding the microbeam peaks. ...

中文翻译：

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通过使用Sm掺杂的氟铝酸盐玻璃板进行大剂量，高分辨率剂量测定和蒙特卡洛输运模拟，对微束放射疗法进行剂量分布和x射线能量优化。

微束放射疗法（MRT）利用高度准直的同步加速器产生的X射线创建高剂量放射的狭窄平面，以治疗肿瘤。单个微束的典型宽度为30–50 µm，相距200–500 µm。在光束中心传递的剂量对微束路径中的细胞具有致命性，大约数百格雷（Gy）。每个微束之间的组织都被保留下来，并有助于修复相邻的受损组织。微束峰内的辐射相互作用，例如光电效应和非相干（原子康普顿）散射，会导致一些剂量被输送到与微束相邻的凹谷区域。随着入射X射线能量的改变，材料内的辐射相互作用会发生变化并影响相互作用的可能性，以及将能量沉积在微束峰周围的山谷区域中的电离粒子（电子）的方向性和能量。...