Phlebotomine sand flies are vectors of Leishmania parasites causing different clinical forms of leishmaniases that represent a serious emerging public health problem worldwide. Mexico harbours a large diversity of sand flies, yet only six species have been considered suspected vectors of Leishmania. The disease has been recorded in 25 states, where the State of Veracruz has recorded the highest number of cases with leishmaniases, although no systematic or epidemiological surveillance studies of Leishmania vectors have been carried out in the region. For that reason, the aim of this study was to perform the molecular detection of Leishmania DNA in phlebotomine sand flies collected from a humid tropical region in Veracruz. We confirmed the presence of Leishmania DNA in eight sand fly species. Sand flies with the highest infection were Psathyromyia aclydifera and Pychodopygus panamensis. This is also the first report of Leishmania DNA in Psathyromyia aclydifera, Psathyromyia carpenteri, Dampfomyia beltrani and Brumptomyia mesai. Our findings highlight the importance of entomological surveys and epidemiological studies, since they enable to determine whether sand fly species may be potential Leishmania vectors in a given area of the Mexico, as transmission dynamics can vary in the different regions.

中文翻译：

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墨西哥韦拉克鲁斯州沙蝇中的婴儿利什曼原虫的分子检测（双翅目：Psychodidae：Phlebotominae）。

竹毒sand是利什曼原虫的媒介物，引起了不同的临床形式的利什曼原虫病，代表了全世界范围内严重的新出现的公共卫生问题。墨西哥的沙蝇种类繁多，但只有六种被认为是利什曼原虫的媒介。该疾病已在25个州记录，该州的韦拉克鲁斯州记录了最多的利什曼病病例，尽管该地区尚未进行利什曼病媒介的系统或流行病学监测研究。因此，本研究的目的是对从韦拉克鲁斯州热带湿润地区采集的毒蛇毒沙蝇中的利什曼原虫DNA进行分子检测。我们确认了八个沙蝇物种中都存在利什曼原虫DNA。感染率最高的沙蝇是沙眼假单胞菌和巴拿马假单胞菌。这也是沙眼衣原体，卡氏假单胞菌，beltdami皮带菌和memp布鲁氏菌中利什曼原虫DNA的首次报道。我们的发现凸显了昆虫学调查和流行病学研究的重要性，因为它们可以确定沙尘蝇物种是否可能是墨西哥特定地区的潜在利什曼原虫病媒，因为传播动态在不同地区可能有所不同。