Balanites aegyptiaca L. is a multipurpose tree distributed in Africa and Middle East. Several parts of B. aegyptiaca have been suggested to have medicinal uses. So far the effect of ecological origin on the nutritional values and biological activities of B. aegyptiaca genotypes is rarely investigated. Further, metabolic profiling and assessment of the functional food value of B. aegyptiaca leaves are far from complete. In this study, biological activities and profiling of primary and secondary metabolites were investigated in the leaves of five B. aegyptiaca provenances collected from Egypt, Sudan, Saudi Arabia, and Yemen. Interestingly, all provenances showed notable antidiabetic, antioxidant, antiprotozoal, antibacterial, antifungal, and anticancer activities. Hierarchical clustering analysis revealed significant variability in the concentrations of individual sugars, organic acids, amino acids, fatty acids, vitamins, phenolics, and minerals among the provenances and these variations were provenance dependent. Medina provenance showed the heights diphenylpicrylhydrazyl (DPPH) scavenging and antifungal activities and was the most powerful against embryonic kidney adenocarcinoma and urinary bladder carcinoma cells. The highest inhibition against Escherichia coli and colon carcinoma cells was observed by Sudan and Cairo provenances. El‐Kharga and Yemen provenances showed the greatest activity against Trypanosoma cruzi and hepatocellular and urinary bladder carcinoma. Therefore, leaves of B. aegyptiaca possess good nutritive and biological capacities and might have potential applications in the food and medical industries. However, the strength of such activities is significantly affected by the provenance.

中文翻译：

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种源对沙漠日期的Balanites aegyptiaca的生物活性植物化学物质以及营养和健康益处的影响。

Balanites aegyptiaca L.是分布在非洲和中东的多用途树。有人建议，埃及双歧杆菌的几个部分具有药用价值。迄今为止，很少研究生态起源对埃及埃及双歧杆菌基因型的营养价值和生物学活性的影响。此外，埃及黑芥子叶的代谢特征分析和功能性食品价值评估还远远没有完成。在这项研究中，研究了五个埃及假单胞菌的叶子的生物活性和主要和次要代谢产物的概况。从埃及，苏丹，沙特阿拉伯和也门收集的物产。有趣的是，所有种源均显示出显着的抗糖尿病，抗氧化剂，抗原生动物，抗菌，抗真菌和抗癌活性。层次聚类分析显示，不同来源之间的单个糖，有机酸，氨基酸，脂肪酸，维生素，酚类和矿物质的浓度存在显着差异，并且这些差异取决于来源。麦地那（Medina）种源显示出高的二苯基吡啶甲基肼基（DPPH）清除和抗真菌活性，并且对胚肾腺癌和膀胱癌细胞具有最强的抵抗力。对大肠杆菌的最高抑制作用苏丹和开罗的起源观察到结肠癌细胞。El‐Kharga和也门的血统显示出对克氏锥虫以及肝细胞和膀胱癌的活性最大。因此，埃及双歧杆菌的叶片具有良好的营养和生物能力，并且可能在食品和医疗行业中具有潜在的应用。但是，这种活动的强度受来源的影响很大。