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Yeast Mycocins: a great potential for application in health.
FEMS Yeast Research ( IF 3.2 ) Pub Date : 2020-05-01 , DOI: 10.1093/femsyr/foaa016
Bruna L Nascimento 1 , Mateus F Delabeneta 1 , Lana Rubia B Rosseto 1 , Daniele S B Junges 1 , Ana Paula Paris 1 , Cristiane Persel 1 , Rinaldo F Gandra 1
Affiliation  

Mycocins have demonstrated inhibition of fungi, bacteria, parasites and viruses, in addition to being studied as epidemiological markers and in the development of vaccines. They are defined as extracellular proteins or glycoproteins with different activities, the main mechanism of action being the inhibition of β-glucan synthesis in the cell wall of sensitive strains. Given the resistance problems created by several microorganisms to agents commonly used in clinical practice, the discovery of new substances with this purpose becomes essential. Mycocins have potential as anti-microbials because they show minimal toxicity and do not present resistance.

中文翻译:

酵母菌霉素:在健康中具有巨大的应用潜力。

除作为流行病学标记和疫苗开发外,霉菌素还显示出对真菌,细菌,寄生虫和病毒的抑制作用。它们被定义为具有不同活性的细胞外蛋白或糖蛋白,主要作用机理是抑制敏感菌株细胞壁中β-葡聚糖的合成。考虑到几种微生物对临床实践中常用的药剂产生的抗药性问题,为此目的发现新物质变得至关重要。霉菌素具有潜在的抗微生物作用,因为它们显示的毒性极小且不具有耐药性。
更新日期:2020-04-10
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