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Differential Effects of Nicotine and Nicotine Withdrawal on Fear Conditioning in Male Rats.
International Journal of Neuropsychopharmacology ( IF 4.8 ) Pub Date : 2020-04-02 , DOI: 10.1093/ijnp/pyaa024
Mykel A Robble 1 , Isaiah L Holloway 1 , Elysia Ridener 1 , Chelsea J Webber 1 , S Barak Caine 1 , Edward G Meloni 1 , Rajeev I Desai 1 , William A Carlezon 1
Affiliation  

Tobacco use is prevalent in individuals who are routinely exposed to stress. However, little is known about how nicotine affects responses to trauma. We examined in rats how nicotine exposure affects fear conditioning, a procedure often used to study stress-related psychiatric illness.

中文翻译:

尼古丁和尼古丁戒断对雄性大鼠恐惧条件反射的不同影响。

烟草使用在经常承受压力的人中很普遍。然而,人们对尼古丁如何影响对创伤的反应知之甚少。我们在大鼠中检查了尼古丁暴露如何影响恐惧条件反射,这是一种常用于研究与压力相关的精神疾病的程序。
更新日期:2020-04-02
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