当前位置: X-MOL 学术Polym. Eng. Sci. › 论文详情
Our official English website, www.x-mol.net, welcomes your feedback! (Note: you will need to create a separate account there.)
Characterization of biodegradable poly(l‐lactide) tube over accelerated degradation
Polymer Engineering and Science ( IF 3.2 ) Pub Date : 2020-04-08 , DOI: 10.1002/pen.25390
Raasti Naseem 1 , Liguo Zhao 1 , Senthil K. Eswaran 2 , Helen Willcock 3
Affiliation  

The next‐generation bioresorbable polymeric stents are undergoing continual research and development, especially how to control and optimize their degradation behaviors. The aim of this paper is to study the properties of a poly(l‐lactide) (PLLA) tube over accelerated degradation in vitro. Spherical nanoindentation was particularly adopted to measure the mechanical properties of PLLA tube; while differential scanning calorimetry and gel permeation chromatography were used for crystallinity and molecular weight measurements. Overall, the material degradation was captured by the local stress‐strain response obtained with spherical nanoindentation, and further confirmed with chemical analyses. The results are particularly useful for development of bioresorbable polymeric stents with improved performance.

中文翻译:

加速降解过程中可生物降解的聚(l-丙交酯)管的表征

下一代生物可吸收聚合物支架正在不断研究和开发,尤其是如何控制和优化其降解行为。本文的目的是研究聚l-丙交酯(PLLA)管在体外加速降解方面的特性。球形纳米压痕特别用于测量PLLA管的力学性能。差示扫描量热法和凝胶渗透色谱法用于结晶度和分子量测量。总体而言,材料降解是通过球形纳米压痕获得的局部应力应变响应捕获的,并通过化学分析进一步证实。该结果对于开发具有改善的性能的可生物吸收的聚合物支架特别有用。
更新日期:2020-04-08
down
wechat
bug