Among 200 patients developing hospital-acquired pneumonia (HAP) outside the intensive care unit, 61% were treated empirically without broad-spectrum Gram-negative coverage, with clinical cure in 69.7%. Lower disease severity markers (systemic inflammatory response syndrome, hypoxia, tachypnoea, neutrophilia) and the absence of diabetes mellitus and prior doxycycline treatment (but not the time to HAP onset) identified patients not requiring broad-spectrum Gram-negative coverage.

中文翻译：

---

医院获得性肺炎的亚组患者不需要广谱革兰氏阴性抗菌药物。

在重症监护病房以外发生医院获得性肺炎（HAP）的200例患者中，有61％接受了经验治疗，没有广谱革兰氏阴性报道，临床治愈率为69.7％。较低的疾病严重性指标（全身性炎症反应综合征，低氧，快速呼吸，嗜中性粒细胞减少）以及没有糖尿病和先前的强力霉素治疗（但不是HAP发作的时间）可确定患者不需要广谱革兰氏阴性报道。