Since its isolation by Esther Lederberg, phage lambda and its repressor protein CI have contributed substantially to the advancement of molecular biology. In this issue of Cell Host & Microbe, Silpe et al. (2020) characterize the antirepressor Qtip of Vibrio phage VP882, which through CI sequestration triggers a lytic switch.

中文翻译：

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噬菌体将抗压制提高到一个新的水平

自从被Esther Lederberg分离以来，噬菌体λ及其阻遏蛋白CI大大促进了分子生物学的发展。在本期《细胞宿主与微生物》中，Silpe等人。（2020）表征了弧菌噬菌体VP882的抗阻遏物Qtip，其通过CI隔离触发了裂解开关。