For poorly understood reasons, Black non‐Hispanic (BNH) women meeting National Comprehensive Cancer Network (NCCN) criteria for genetic testing for breast cancer risk are less likely than White non‐Hispanic (WNH) women to undergo testing (Armstrong, Micco, Carney, Stopfer, & Putt, JAMA, 293, 1729 and 2005). We compared physician referral rates and uptake for genetic testing of BNH and WNH women meeting select NCCN criteria (breast cancer under age 50, two primary breast cancers, triple‐negative disease under age 60) in the Cancer Center at George Washington University (GWCC) between 2015 and 2018. Of the 723 BNH and WNH patients treated for breast cancer at GWCC, 28% met study criteria for genetic counseling referral (n  = 252; BNH n  = 115, WNH n  = 137). Physician referral rates to genetic counseling differed significantly by race (BNH 75.7%, n  = 87 and WNH 92.7%; n  = 127; χ² = 14.19, p‐value < .01). Once referred, though, there was no significant difference in uptake of genetic counseling by race (BNH 95.4%, n  = 83; WNH 97.6%, n  = 124, χ² = 1.33, p‐value = .25) for patients appropriately referred.

中文翻译：

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乳腺癌遗传风险评估推荐中的种族差异。

出于不为人所知的原因，达到国家综合癌症网络（NCCN）乳腺癌风险基因检测标准的非西班牙裔黑人（BNH）妇女比接受白人非西班牙裔（WNH）妇女进行检查的可能性较小（Armstrong，Micco和Carney ，Stopfer，＆Putt，JAMA，293，1729和2005）。我们比较了乔治华盛顿大学（GWCC）癌症中心符合部分NCCN标准（50岁以下的乳腺癌，两种原发性乳腺癌，60岁以下的三阴性疾病）的BNH和WNH妇女的基因检测的转诊率和摄取率。在2015年至2018年之间。在GWCC接受乳腺癌治疗的723名BNH和WNH患者中，有28％符合遗传咨询转诊的研究标准（n  = 252； BNH n  = 115，WNH n = 137）。医师转诊率到遗传咨询由人种显著差异（BNH 75.7％，Ñ  = 87和WNH 92.7％; Ñ  = 127;χ ²  = 14.19，p值<0.01）。曾经提到，虽然有在遗传咨询的摄取没有种族差异显著（BNH 95.4％，Ñ  = 83; WNH 97.6％，Ñ  = 124，χ ²  = 1.33，p -值= 0.25）的患者适当称为。