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CD16high CD62Ldim neutrophils induce nerve mediated airway hyperreactivity
Clinical & Experimental Allergy ( IF 6.1 ) Pub Date : 2020-04-14 , DOI: 10.1111/cea.13602
Sandra Ekstedt 1 , Olivia Larsson 1 , Susanna Kumlien Georén 1 , Lars Olaf Cardell 1, 2
Affiliation  

Inflammatory cells, such as neutrophils, eosinophils and mast cells are found in the airways and lungs of asthmatic patients. Generally, eosinophils and mast cells have been given more attention in allergic asthma than neutrophils. Eosinophils and mast cells are known to contribute to chronic inflammation, airway obstruction and hyperresponsiveness. The neutrophils have been easy to overlook, as they are present in the lung at all times, even in non-symptomatic asthmatic patients.

中文翻译:

CD16high CD62Ldim 中性粒细胞诱导神经介导的气道高反应性

在哮喘患者的气道和肺中发现炎性细胞,例如中性粒细胞、嗜酸性粒细胞和肥大细胞。一般来说,嗜酸性粒细胞和肥大细胞在过敏性哮喘中比中性粒细胞受到更多关注。已知嗜酸性粒细胞和肥大细胞会导致慢性炎症、气道阻塞和高反应性。中性粒细胞很容易被忽视,因为它们一直存在于肺部,即使在无症状的哮喘患者中也是如此。
更新日期:2020-04-14
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