Tanshinone I (Tan‐I) is one of the vital fatsoluble monomer components, which extracted from Chinese medicinal herb Salvia miltiorrhiza Bunge. It has been shown that Tan‐I exhibited anti‐tumour activities on different types of cancers. However, the underlying mechanisms by which Tan‐Ⅰ regulates apoptosis and autophagy in ovarian cancer remain unclear. Thus, this study aimed to access the therapy effect of Tan‐Ⅰ and the underlying mechanisms.

中文翻译：

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丹参酮 I 通过 PI3K/AKT/mTOR 通路的失活诱导细胞凋亡和自噬减弱卵巢癌的恶性生物学特性

丹参酮 I (Tan-I) 是重要的脂溶性单体成分之一，从中药丹参中提取。研究表明，Tan-I 对不同类型的癌症表现出抗肿瘤活性。然而，Tan-Ⅰ调节卵巢癌细胞凋亡和自噬的潜在机制尚不清楚。因此，本研究旨在了解 Tan-Ⅰ的治疗效果及其潜在机制。