Eukaryotic origins are inextricably linked with the arrival of a pre‐mitochondrion of alphaproteobacterial‐like ancestry. However, the nature of the “host” cell and the mode of entry are subject to heavy debate. It is becoming clear that the mutual adaptation of a relatively simple, archaeal host and the endosymbiont has been the defining influence at the beginning of the eukaryotic lineage; however, many still resist such symbiogenic models. In part 1, it is posited that a symbiotic stage before uptake (“pre‐symbiosis”) seems essential to allow further metabolic integration of the two partners ending in endosymbiosis. Thus, the author argued against phagocytic mechanisms (in which the bacterium is prey or parasite) as the mode of entry. Such positions are still broadly unpopular. Here it is explained why. Evolutionary thinking, especially in the case of eukaryogenesis, is still dominated by anachronistic reasoning, in which highly derived protozoan organisms are seen as in some way representative of intermediate steps during eukaryotic evolution, hence poisoning the debate. This reasoning reflects a mind‐set that ignores that Darwinian evolution is a fundamentally historic process. Numerous examples of this kind of erroneous reasoning are given, and some basic precautions against its use are formulated. Also see the video abstract here https://youtu.be/ekqtNleVJpU

中文翻译：

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辩论真核发生——第 2 部分：不合时宜的推理如何诱使我们发明中间体

真核生物的起源与类α-变形菌祖先的前线粒体的到来有着千丝万缕的联系。然而，“宿主”细胞的性质和进入方式引起了激烈的争论。越来越清楚的是，相对简单的古菌宿主和内共生体的相互适应一直是真核谱系开始时的决定性影响。然而，许多人仍然抵制这种共生模型。在第 1 部分中，假设摄取前的共生阶段（“预共生”）似乎是允许两个伙伴进一步代谢整合以内共生结束的必要条件。因此，作者反对将吞噬机制（其中细菌是猎物或寄生虫）作为进入方式。这些职位仍然普遍不受欢迎。这里解释了原因。进化思维，特别是在真核发生的情况下，仍然以不合时宜的推理为主导，其中高度衍生的原生动物生物在某种程度上被视为真核进化过程中的中间步骤的代表，因此引发了争论。这种推理反映了一种思维定势，即忽视了达尔文进化论是一个根本性的历史过程。给出了这种错误推理的许多例子，并制定了一些防止使用它的基本预防措施。另请参阅此处的视频摘要 https://youtu.be/ekqtNleVJpU 这种推理反映了一种思维定势，即忽视了达尔文进化论是一个根本性的历史过程。给出了这种错误推理的许多例子，并制定了一些防止使用它的基本预防措施。另请参阅此处的视频摘要 https://youtu.be/ekqtNleVJpU 这种推理反映了一种思维定势，即忽视了达尔文进化论是一个根本性的历史过程。给出了这种错误推理的许多例子，并制定了一些防止使用它的基本预防措施。另请参阅此处的视频摘要 https://youtu.be/ekqtNleVJpU