The aim was to evaluate remineralization capacity and antibacterial efficiency of Tooth Mousse and various amounts of glycyrrhizic acid added Tooth Mousse on primary tooth enamel. Three groups were formed; Group 1 (CPP‐ACP), Group 2 (CPP‐ACP + 5% glycyrrhizic acid), and Group 3 (CPP‐ACP + 10% glycyrrhizic acid) in order to evaluate remineralization capacity. Enamel samples were immersed in demineralization solution and then remineralization agents were applied. Surface microhardness and SEM analyses were performed at the beginning, after demineralization and remineralization. For antibacterial tests, four groups were formed; Group 1, Group 2 and Group 3 and Group 4 (control). Biofilms were then exposed to 10% sucrose eight times per day for 7 days. After biofilm growth period, samples were treated with materials to evaluate antibacterial efficiency except control group. After application of materials, samples were incubated 2 more days at 37°C and at the end of this period, absorbance values of biofilms were determined and data were analyzed. An increase in microhardness values was Group 2 > Group 3 > Group 1, respectively, but there were no significant differences. After remineralization, microhardness values showed significant increases when compared to demineralized groups, but there was no significant difference. All groups showed decreased absorbance value of biofilm when compared with control group but they were insignificant. It was observed that both in Group 2 and Group 3, glycyrrhizic acid did not have a negative effect on remineralization and although they have an increase, it was insignificant. Although glycyrrhizic acid added CPP‐ACP groups showed increased antibacterial activity, they were not statistically significant.

中文翻译：

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甘草酸加酪蛋白磷酸肽-无定形磷酸钙的抗菌功效和再矿化能力。

目的是评估牙齿摩丝的再矿化能力和抗菌效率，以及在初级牙釉质上添加了不同量的甘草酸的牙齿摩丝。形成了三个小组。第1组（CPP‐ACP），第2组（CPP‐ACP + 5％甘草酸）和第3组（CPP‐ACP + 10％甘草酸）以评估再矿化能力。将搪瓷样品浸入去矿物质溶液中，然后再施加矿化剂。在脱矿质和再矿化之后，首先进行表面显微硬度和SEM分析。为了进行抗菌测试，形成了四组。第1组，第2组，第3组和第4组（控制）。然后每天将生物膜暴露于10％的蔗糖中八次，共7天。在生物膜生长期之后，用材料处理样品以评估除对照组外的抗菌效率。施用材料后，将样品在37°C下再温育2天，在此期间结束时，确定生物膜的吸光度值并分析数据。显微硬度值的增加分别为组2>组3>组1，但没有显着差异。再矿化后，与去矿化组相比，显微硬度值显着提高，但无显着差异。与对照组相比，所有组的生物膜吸收值均降低，但无统计学意义。据观察，在第2组和第3组中，甘草酸对再矿化没有负面影响，尽管增加了，但微不足道。尽管添加了甘草酸的CPP-ACP组显示出增强的抗菌活性，但它们在统计学上并不显着。