ABSTRACT The number and use of medicines based on natural products such as plants have increased as scientific evidence indicates that they have various bioactive compounds with biological activities. This study determined the content of five phenolic compounds and two major steviol glucosides in S. rebaudiana (INIFAP-C01 variety): Extracts from Muna: aqueous and ethanolic extracts of leaves and stems (HAMU and HEMU) (TAMU and TEMU); and extracts from Mocochá: aqueous and ethanolic extracts of leaves and stems (HAMO and HEMO) (TAMO and TEMO). The HEMU extract had a higher content of phenolic compounds (2.23 g/100g) and major steviol glucosides (17.12 g/100g). HEMU and HEMO extracts showed a higher inhibition of Angiotensin-Converting Enzyme (ACE) activity (95.04% and 91.73%, respectively), α-amylase activity (52.85% and 86.78%, respectively), and α-glucosidase activity (94.53% and 91.73%, respectively). Furthermore, HEMU and HEMO extracts showed higher antioxidant capacities (79.95% and 76.64%, respectively), and the HEMU extract achieved a Trolox Equivalent Antioxidant Capacity (TEAC) value of 174 mol/g. Creole variety (INIFAP C01) S. rebaudiana has phytochemicals able to help promote health, inhibit enzymes in metabolism, and provide antioxidant protection.

中文翻译：

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酚类化合物和主要甜菊糖苷的 HPLC-DAD-RP 和叶和茎的水和乙醇提取物的生物活性的体外评估：S. rebaudiana Bertoni（克里奥尔品种 INIFAP C01）

摘要 以植物等天然产品为基础的药物的数量和使用有所增加，因为科学证据表明它们具有各种具有生物活性的生物活性化合物。本研究确定了甜叶菊（INIFAP-C01 品种）中五种酚类化合物和两种主要甜菊糖苷的含量： Muna 提取物：叶和茎（HAMU 和 HEMU）（TAMU 和 TEMU）的水和乙醇提取物；和 Mocochá 提取物：叶子和茎（HAMO 和 HEMO）（TAMO 和 TEMO）的水和乙醇提取物。HEMU 提取物的酚类化合物 (2.23 g/100g) 和主要甜菊糖苷 (17.12 g/100g) 含量更高。HEMU 和 HEMO 提取物对血管紧张素转换酶 (ACE) 活性（分别为 95.04% 和 91.73%）、α-淀粉酶活性（分别为 52.85% 和 86.78%）、和 α-葡萄糖苷酶活性（分别为 94.53% 和 91.73%）。此外，HEMU 和 HEMO 提取物显示出更高的抗氧化能力（分别为 79.95% 和 76.64%），并且 HEMU 提取物实现了 174 mol/g 的 Trolox 等效抗氧化能力 (TEAC) 值。克里奥尔品种 (INIFAP C01) S. rebaudiana 的植物化学物质能够帮助促进健康、抑制新陈代谢中的酶并提供抗氧化保护。