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Histological characterization of the lingual tonsils of the one-humped camel (Camelus dromedarius)
Cell and Tissue Research ( IF 3.6 ) Pub Date : 2019-12-06 , DOI: 10.1007/s00441-019-03135-2
Mohamed Zidan , Reinhard Pabst

Tonsils are located in the entrance of digestive and respiratory tracts forming Waldeyer’s ring that reacts against ingested or inhaled antigens. On occasion, tonsils may be a site of entry and replication for some pathogens. The lingual tonsils are a main constituent of the Waldeyer’s ring. Despite the immunological importance of the lingual tonsils, there is limited information about their structure in the one-humped camel. The lingual tonsils of 10 clinically healthy male camels (3–25 years) were collected and studied macroscopically and microscopically. Lingual tonsils were localized at the root of the tongue of camels of all ages in the form of several spherical macroscopic nodules protruding into the oropharynx. Each nodule possesses a single central crypt, covered with keratinized stratified squamous epithelium without any M cells and surrounded with an incomplete capsule. Each tonsillar crypt was lined with stratified squamous non-keratinized epithelium with lymphocytic infiltration forming patches of lymphoepithelium or reticular epithelium. Secondary lymphoid nodules extended under the apical epithelium. The interfollicular areas had diffused lymphocytes. Among these lymphocytes, high endothelial venules, macrophages, dendritic cells and plasma cells were observed. The organization of camel lingual tonsils in isolated units with separate crypts increases the surface area exposed to antigen. The present findings indicate a sustained immunological role of the lingual tonsils throughout the life of the one-humped camel.

中文翻译:

单峰骆驼(Camelus dromedarius)舌扁桃体的组织学特征

扁桃体位于消化道和呼吸道的入口,形成 Waldeyer 环,对摄入或吸入的抗原起反应。有时,扁桃体可能是某些病原体进入和复制的部位。舌扁桃体是 Waldeyer 环的主要组成部分。尽管舌扁桃体具有免疫学重要性,但关于它们在单峰骆驼中的结构的信息有限。收集了 10 头临床健康雄性骆驼(3-25 岁)的舌侧扁桃体,并进行了宏观和微观研究。舌扁桃体位于所有年龄的骆驼舌根处,呈几个球形的宏观结节,突出到口咽部。每个结节都有一个中央隐窝,被角化的复层鳞状上皮覆盖,没有任何 M 细胞,被不完整的被膜包围。每个扁桃体隐窝内衬复层鳞状非角化上皮,淋巴细胞浸润形成淋巴上皮或网状上皮斑块。继发性淋巴结节在顶端上皮下延伸。滤泡间区域有扩散的淋巴细胞。在这些淋巴细胞中,观察到高内皮微静脉、巨噬细胞、树突细胞和浆细胞。骆驼舌扁桃体在具有独立隐窝的隔离单位中的组织增加了暴露于抗原的表面积。目前的研究结果表明,在单峰骆驼的整个生命周期中,舌扁桃体具有持续的免疫作用。每个扁桃体隐窝内衬复层鳞状非角化上皮,淋巴细胞浸润形成淋巴上皮或网状上皮斑块。继发性淋巴结节在顶端上皮下延伸。滤泡间区域有扩散的淋巴细胞。在这些淋巴细胞中,观察到高内皮微静脉、巨噬细胞、树突细胞和浆细胞。骆驼舌扁桃体在具有独立隐窝的隔离单位中的组织增加了暴露于抗原的表面积。目前的研究结果表明,在单峰骆驼的整个生命周期中,舌扁桃体具有持续的免疫作用。每个扁桃体隐窝内衬复层鳞状非角化上皮,淋巴细胞浸润形成淋巴上皮或网状上皮斑块。继发性淋巴结节在顶端上皮下延伸。滤泡间区域有扩散的淋巴细胞。在这些淋巴细胞中,观察到高内皮微静脉、巨噬细胞、树突细胞和浆细胞。骆驼舌扁桃体在具有独立隐窝的隔离单位中的组织增加了暴露于抗原的表面积。目前的研究结果表明,在单峰骆驼的整个生命周期中,舌扁桃体具有持续的免疫作用。滤泡间区域有扩散的淋巴细胞。在这些淋巴细胞中,观察到高内皮微静脉、巨噬细胞、树突细胞和浆细胞。骆驼舌扁桃体在具有独立隐窝的隔离单位中的组织增加了暴露于抗原的表面积。目前的研究结果表明,在单峰骆驼的整个生命周期中,舌扁桃体具有持续的免疫作用。滤泡间区域有扩散的淋巴细胞。在这些淋巴细胞中,观察到高内皮微静脉、巨噬细胞、树突细胞和浆细胞。骆驼舌扁桃体在具有独立隐窝的隔离单位中的组织增加了暴露于抗原的表面积。目前的研究结果表明,在单峰骆驼的整个生命周期中,舌扁桃体具有持续的免疫作用。
更新日期:2019-12-06
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