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Extracellular ionic fluxes suggest the basis for cellular life at the 1/f ridge of extended criticality.
European Biophysics Journal ( IF 2 ) Pub Date : 2020-03-24 , DOI: 10.1007/s00249-020-01430-3
Mariusz Pietruszka 1 , Monika Olszewska 1
Affiliation  

The criticality hypothesis states that a system may be poised in a critical state at the boundary between different types of dynamics. Previous studies have suggested that criticality has been evolutionarily selected, and examples have been found in cortical cell cultures and in the human nervous system. However, no one has yet reported a single- or multi-cell ensemble that was investigated ex vivo and found to be in the critical state. Here, the precise 1/f noise was found for pollen tube cells of optimum growth and for the physiological ("healthy") state of blood cells. We show that the multi-scale processes that arise from the so-called critical phenomena can be a fundamental property of a living cell. Our results reveal that cell life is conducted at the border between order and disorder, and that the dynamics themselves drive a system towards a critical state. Moreover, a temperature-driven re-entrant state transition, manifest in the form of a Lorentz resonance, was found in the fluctuation amplitude of the extracellular ionic fluxes for the ensemble of elongating pollen tubes of Nicotiana tabacum L. or Hyacintus orientalis L. Since this system is fine-tuned for rapid expansion to reach the ovule at a critical temperature which results in fertilisation, the core nature of criticality (long-range coherence) offers an explanation for its potential in cell growth. We suggest that the autonomous organisation of expansive growth is accomplished by self-organised criticality, which is an orchestrated instability that occurs in an evolving cell.

中文翻译:

细胞外离子通量提示了细胞在延长临界的1 / f处的寿命。

关键性假设指出,系统可能处于关键状态,处于不同类型的动力学之间的边界。先前的研究表明,对关键性进行了进化选择,并在皮质细胞培养物中和人的神经系统中发现了实例。但是,还没有人报告过离体研究的单细胞或多细胞集合体,发现其处于临界状态。在此,对于最佳生长的花粉管细胞和血细胞的生理(“健康”)状态,发现了精确的1 / f噪声。我们表明,由所谓的临界现象引起的多尺度过程可能是活细胞的基本属性。我们的结果表明,细胞生命是在有序和无序之间进行的,动态本身将系统推向临界状态。此外,在烟叶或Hyacintus Orientalis L的延长花粉管集合中,在细胞外离子通量的波动幅度中发现了以洛伦兹共振形式表现的温度驱动的折返状态转变。该系统经过微调,可以在临界温度下快速扩增以到达胚珠,从而导致受精。临界的核心性质(长距离连贯性)为其在细胞生长中的潜力提供了解释。我们建议通过自组织的临界来完成膨胀增长的自主组织,这是在不断发展的细胞中发生的精心策划的不稳定性。表现为Lorentz共振形式的明显信号,是在烟草(Nicotiana tabacum L.或Hyacintus Orientalis L)的延长花粉管集合的细胞外离子通量的波动幅度中发现的。由于对该系统进行了微调,可以快速扩展以达到在导致受精的临界温度下的胚珠,临界(远距离连贯性)的核心性质为其在细胞生长中的潜力提供了解释。我们建议通过自组织的临界来完成膨胀性增长的自主组织,这种自组织的临界是在不断发展的细胞中发生的精心策划的不稳定性。表现为Lorentz共振形式的明显信号,是在烟草(Nicotiana tabacum L.或Hyacintus Orientalis L)的延长花粉管集合的细胞外离子通量的波动幅度中发现的。在导致受精的临界温度下的胚珠,临界(远距离连贯性)的核心性质为其在细胞生长中的潜力提供了解释。我们建议通过自组织的临界来完成膨胀性增长的自主组织,这种自组织的临界是在不断发展的细胞中发生的精心策划的不稳定性。由于对该系统进行了微调,可在临界温度下快速扩增以达到胚珠,从而导致受精,因此临界性(长距离连贯性)的核心性质为其在细胞生长中的潜力提供了解释。我们建议通过自组织的临界来完成膨胀增长的自主组织,这是在不断发展的细胞中发生的精心策划的不稳定性。由于对该系统进行了微调,可在临界温度下快速扩增以达到胚珠,从而导致受精,因此临界性(长距离连贯性)的核心性质为其在细胞生长中的潜力提供了解释。我们建议通过自组织的临界来完成膨胀性增长的自主组织,这种自组织的临界是在不断发展的细胞中发生的精心策划的不稳定性。
更新日期:2020-04-21
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