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Successful Pregnancy after Intervention for Spindle-Cell Embryonal Rhabdomyosarcoma: A Case Report.
Journal of Pediatric and Adolescent Gynecology ( IF 1.8 ) Pub Date : 2020-03-26 , DOI: 10.1016/j.jpag.2020.03.004
Sara M Moufarrij 1 , Creighton Edwards 2 , Laurie McKenzie 3 , Oluyemisi Adeyemi-Fowode 4
Affiliation  

Background

Embryonal rhabdomyosarcoma, the most common soft tissue malignancy in childhood, is treated with surgery and chemotherapy. Because of the young age at the time of presentation, a discussion of future reproduction is appropriate and conservative management should be considered. We present a case of embryonal rhabdomyosarcoma that was successfully and conservatively managed with chemotherapy, allowing for future pregnancies.

Case

A 17-year-old nulliparous woman with embryonal rhabdomyosarcoma underwent 6 cycles of chemotherapy with adriamycin, dacarbazine, cyclophosphamide, and vincristine, resulting in radiographic resolution of the disease. She was able to conceive without medical intervention and to have successful vaginal deliveries.

Summary and Conclusion

The standard of care for embryonal rhabdomyosarcoma is surgery and chemotherapy; however, conservative management should be considered when preservation of fertility is a goal.



中文翻译:

主轴细胞胚胎横纹肌肉瘤介入治疗后成功妊娠:一例报告。

背景

胚胎横纹肌肉瘤是儿童期最常见的软组织恶性肿瘤,可通过手术和化学疗法进行治疗。由于在发表时年龄太小,因此对未来生殖的讨论是适当的,应考虑保守管理。我们介绍了一例成功治疗并保守治疗的胚胎性横纹肌肉瘤,以备将来怀孕。

案件

一名患有胚胎性横纹肌肉瘤的17岁未产妇妇女接受了6个周期的阿霉素,达卡巴嗪,环磷酰胺和长春新碱的化疗,从而对该病进行了放射学分辨。她能够在没有医疗干预的情况下受孕,并且能够成功分娩。

总结与结论

胚胎横纹肌肉瘤的治疗标准是手术和化疗。但是,当以保持生育力为目标时,应考虑采取保守管理。

更新日期:2020-03-26
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