Huastecos or Teenek Amerindians are presently living at North East Mexico (San Luis Potosi State). They have probably one of the most ancient culture of Mexico and Central America together with Mayas and Olmec groups with which also show close relationships. Proximity to Atlantic Ocean/Mexican Gulf originated that Spaniards had very early contact with them at about 1519 CE or before. In the present paper we have aimed to study HLA gene profile which may be useful for HLA and disease epidemiology and transplant programs in Teeneks. HLA-DRB1*04:07, -DRB1*14:06 and -DRB1*04:11 have been found in high frequency like in other Amerindian groups. High frequency typical Amerindians HLA extended haplotypes have been found, such as A*02-B*35-DRB1*04:07-DQB1*03:02; A*68-B*39-DRB1*04:07-DQB1*03:02 and A*02-B*39-DRB1*04:07-DQB1*03:02; also new haplotypes have been described, like A*02-B*52-DRB1*04:11-DQB1*03:02, A*68-B*35-DRB1*14:02-DQB1*03:01 and A*68-B*40-DRB1*16:02-DQB1*03:01. Genetic proximity is observed not only to linguistically close Mayans, but also to Mazatecans, Mixtecans and Zapotecans, who speak an altogether different languages; it shows once more that genes and languages do not correlate. This population was greatly diminished after European contact between 1500 and 1600 years CE; in fact, North and South America First Inhabitants population was brought from 80 down to 8 million people because of diseases (i.e.: measles, smallpox or influenza), slavery and war.

中文翻译：

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墨西哥San Vicente Tancuayalab Teenek / Huastecos的美洲印第安人中的HLA基因。

Huastecos或Teenek美国印第安人目前居住在墨西哥东北部（圣路易斯波托西州）。他们可能是墨西哥和中美洲最古老的文化之一，与玛雅人和奥尔梅克人群体也有着密切的联系。西班牙人接近大西洋/墨西哥湾的原因是，西班牙人在公元1519年左右或更早就与他们接触。在本文中，我们旨在研究HLA基因谱，这可能对Teeneks中的HLA和疾病流行病学以及移植计划有用。像其他美洲印第安人群体一样，已高频率地发现了HLA-DRB1 * 04：07，-DRB1 * 14：06和-DRB1 * 04：11。已发现高频典型的美洲印第安人HLA扩展单倍型，例如A * 02-B * 35-DRB1 * 04：07-DQB1 * 03：02；A * 68-B * 39-DRB1 * 04：07-DQB1 * 03：02和A * 02-B * 39-DRB1 * 04：07-DQB1 * 03：02; 还描述了新的单倍型，例如A * 02-B * 52-DRB1 * 04：11-DQB1 * 03：02，A * 68-B * 35-DRB1 * 14：02-DQB1 * 03：01和A * 68-B * 40-DRB1 * 16：02-DQB1 * 03：01。不仅在语言上接近玛雅人，而且与说完全不同语言的Mazatecans，Mixtecans和Zapotecans都有亲缘关系。它再次表明基因和语言不相关。在欧洲与公元1500年至1600年之间接触之后，这一人口大大减少了。实际上，由于疾病（例如麻疹，天花或流行性感冒），奴隶制和战争，北美和南美的原住民人口从80下降到800万人。还要说两种不同语言的Mazatecans，Mixtecans和Zapotecans；它再次表明基因和语言不相关。在欧洲与公元1500年至1600年之间接触之后，这一人口大大减少了。实际上，由于疾病（例如麻疹，天花或流行性感冒），奴隶制和战争，北美和南美的原住民人口从80下降到800万人。还要说两种不同语言的Mazatecans，Mixtecans和Zapotecans；它再次表明基因和语言不相关。在欧洲与公元1500年至1600年之间接触之后，这一人口大大减少了。实际上，由于疾病（例如麻疹，天花或流行性感冒），奴隶制和战争，北美和南美的原住民人口从80下降到800万人。