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Contributing risk factors towards the prevalence of multidrug-resistant tuberculosis in Malaysia: A Systematic Review
Tuberculosis ( IF 3.2 ) Pub Date : 2020-05-01 , DOI: 10.1016/j.tube.2020.101925
Mahindran Rajendran 1 , Rafdzah Ahmad Zaki 1 , Nasrin Aghamohammadi 1
Affiliation  

Multidrug-resistant tuberculosis (MDR-TB) is one of the causes of morbidity and mortality, among tuberculosis (TB) patients in Malaysia. The purpose of this study was to determine the contributing risk factors to the prevalence of (MDR-TB). Based on systematic review of the literatures, the prevalence of (MDR-TB) and associated risk factors in Malaysia were studied. A comprehensive search of Scopus, Science direct, PubMed, DOAJ, CINAHL Plus, MyJournal, BIREME, BMC Public Health, Medline, CAB, and WoS databases were done among the articles published from 31st January 2009 to 31st December 2018, by using medical subject heading (MeSH) key terms. In conducting this study, a total of 121 papers were reviewed and 23 research papers were chosen, because, they met the specific inclusion criteria. In this study, gender, age, marital status, ethnicity, homeless status, living in urban area and history of imprisonment were evaluated as demographic factors, while educational level and employment were evaluated as socioeconomic factors. Smoking, diabetes mellitus, drug abuse and alcohol consumption were evaluated as behavioral and co-morbidities factors. All the studies chosen as eligible to be included in this study were found to be significantly associated with the risk factors for the prevalence of (MDR-TB). It was also discovered that, lack of adequate knowledge among the community and (TB) patients might increase the progression of (MDR-TB) infection in Malaysia. Thus, carried out a systematic review provided a comprehensive assessment of the (MDR-TB) which might be useful for policy makers, health experts and researchers to implement appropriate strategies for (TB) infected population in Malaysia.

中文翻译:

导致马来西亚耐多药结核病流行的危险因素:系统评价

耐多药结核病 (MDR-TB) 是马来西亚结核病 (TB) 患者发病率和死亡率的原因之一。本研究的目的是确定导致(耐多药结核病)流行的危险因素。在系统回顾文献的基础上,研究了马来西亚(耐多药结核病)的患病率和相关危险因素。使用医学主题对 2009 年 1 月 31 日至 2018 年 12 月 31 日发表的文章中的 Scopus、Science direct、PubMed、DOAJ、CINAHL Plus、MyJournal、BIREME、BMC Public Health、Medline、CAB 和 WoS 数据库进行全面搜索标题 (MeSH) 关键术语。在进行这项研究时,总共审查了 121 篇论文,并选择了 23 篇研究论文,因为它们符合特定的纳入标准。在本研究中,性别、年龄、婚姻状况、种族、无家可归状况、居住在城市地区和监禁历史作为人口因素进行评估,而教育水平和就业作为社会经济因素进行评估。吸烟、糖尿病、药物滥用和饮酒被评估为行为和合并症因素。发现所有被选为有资格纳入本研究的研究都与 (MDR-TB) 流行的危险因素显着相关。还发现,社区和(TB)患者缺乏足够的知识可能会增加马来西亚(MDR-TB)感染的进展。因此,进行的系统评价提供了对(耐多药结核病)的综合评估,这可能对决策者有用,
更新日期:2020-05-01
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