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Side-viewing photoacoustic waveguide endoscopy.
Photoacoustics ( IF 7.9 ) Pub Date : 2020-03-10 , DOI: 10.1016/j.pacs.2020.100167
Christopher Miranda 1 , Ethan Marschall 1 , Blake Browning 1 , Barbara S Smith 1
Affiliation  

Side-viewing hollow optical waveguides allow for minimally invasive endoscopy by concentrically guiding light and sound for photoacoustic generation and detection. Here, we characterize the side-viewing photoacoustic waveguide (PWG) endoscope by scanning 7.2 μm diameter carbon fiber threads within phantom tissues and animal tissues. Photoacoustic signals are carried along the 5.5 and 10.0 cm length of the PWG with minimal attenuation. Thus, this technology enables 360°, deep-tissue photoacoustic imaging. Photoacoustic signals were identified up to 8.0 mm from the PWG imaging window in an optically clear medium. The outer diameter of this device is measured as just over 1.0 mm, with the potential to be further miniaturized due to its unique design. The PWG is an ideal candidate for a myriad of pre-clinical and clinical applications where typical photoacoustic endoscopy systems are impractical, due to their size. Presented here, is the first side-viewing photoacoustic waveguide endoscope.



中文翻译:

侧视光声波导内窥镜。

侧视中空光波导通过同心引导光和声音进行光声生成和检测,从而实现微创内窥镜检查。在这里,我们通过扫描幻体组织和动物组织内的 7.2 μm 直径碳纤维线来表征侧视光声波导 (PWG) 内窥镜。光声信号沿着 PWG 的 5.5 和 10.0 cm 长度传输,衰减最小。因此,该技术能够实现 360° 深层组织光声成像。在光学透明介质中,从 PWG 成像窗口最远 8.0 mm 处识别出光声信号。该设备的外径经测量仅超过 1.0 毫米,由于其独特的设计,有可能进一步小型化。PWG 是众多临床前和临床应用的理想选择,在这些应用中,典型的光声内窥镜系统由于其尺寸而无法实用。这里展示的是第一台侧视光声波导内窥镜。

更新日期:2020-03-10
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