Background

Hydrogen sulfide is the final product of sulfate-reducing bacteria metabolism. Its high concentration in the gut can affect adversely bowel environment and intestinal microbiota by toxicity and pH lowering.

Aim of Review

The aim of the review was to give observations related to the properties of bacterial communities inhabiting the gut, with the emphasis on sulfate-reducing bacteria and lactic acid bacteria.

Key Scientific Concepts of Review

The conduction of meta-analysis was another goal, since it gave statistical observation of the relevant studies. The review literature consisted of more than 160 studies, published from 1945 to 2019. Meta-analysis included 16 studies and they were chosen from the Web of Science database. The systematic review gave important information about the development of gut inflammation, with emphasis on sulfate-reducing and lactic acid bacteria. Oppositely from sulfate-reducing bacteria, probiotic properties of lactic acid bacteria are effective inhibitors against inflammatory bowel disease development, including ulcerative colitis. These facts were confirmed by the conducted meta-analysis. The results and observations gained from the systematic review represent the emphasized importance of gut microbiota for bowel inflammation. On the other side, it should be stated that more studies in the future will provide even better confirmations.

中文翻译：

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肠道环境中的硫化氢毒性：硫酸盐还原菌和乳酸菌在炎症过程中的荟萃分析

背景

硫化氢是硫酸盐还原菌代谢的最终产物。它在肠道中的高浓度会通过毒性和 pH 值降低对肠道环境和肠道微生物群产生不利影响。

审查目的

该综述的目的是提供与肠道内细菌群落特性相关的观察结果，重点是硫酸盐还原菌和乳酸菌。

审查的关键科学概念

进行荟萃分析是另一个目标，因为它可以对相关研究进行统计观察。综述文献由 1945 年至 2019 年发表的 160 多项研究组成。荟萃分析包括 16 项研究，它们选自 Web of Science 数据库。系统评价提供了有关肠道炎症发展的重要信息，重点是硫酸盐还原菌和乳酸菌。与硫酸盐还原菌相反，乳酸菌的益生菌特性可以有效抑制炎症性肠病的发展，包括溃疡性结肠炎。这些事实已通过荟萃分析得到证实。从系统评价中获得的结果和观察结果强调了肠道微生物群对肠道炎症的重要性。另一方面，应该说，未来更多的研究将会提供更好的证实。