Virus exploits host cellular machinery to replicate and form new viral progeny and endoplasmic reticulum (ER) plays central role in the interplay between virus and host cell. Here I will discuss how cellular functions of ER being utilized by viruses from different families during different stages of pathogenesis. Flow of knowledge related to this area of research based on interdisciplinary approach, using biochemical and cell biological assays coupled with advanced microscopy strategies, is pushing our understanding of the virus-ER interaction during infection to the next level.

中文翻译：

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内质网在病毒感染中。

病毒利用宿主细胞机制复制并形成新的病毒后代，内质网（ER）在病毒与宿主细胞之间的相互作用中起着核心作用。在这里，我将讨论在发病机理的不同阶段，来自不同家族的病毒如何利用ER的细胞功能。基于跨学科方法的这一研究领域的知识流，结合使用生化和细胞生物学分析以及先进的显微镜策略，将我们对感染期间病毒-ER相互作用的理解推向了新的高度。