Abstract Synthesis and biomedical research of bimetallic gold-silver nanoparticles (Au–Ag NPs) have gained much attention due to their unique properties. Antibacterial mechanism of gold-silver nanoparticles is a current topic of interest in nanomedicine engineering. We used three routes in the synthesis of Au–Ag NPs alloy: i) Co-reduction of [HOOC-4-C6H4N N]AuCl4/AgNO3, ii) Seeding of AuNPs-COOH/AgNO3 and iii) immobilization of AgNPs over the parent AuNPs-COOH. Two mild reducing agents, NaBH4 and 9-BBN (9-borabicyclo(3.3.1)nonane), were used. Colloidal alloy nanoparticles structure was confirmed using transmission electron microscopy (TEM) and X-ray photoelectron spectroscopy (XPS). The particles reduced using NaBH4 were larger (~20 nm) than those synthesized using 9-BBN (

中文翻译：

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从金银合金纳米粒子中按需释放离子银：基本抗菌机制研究

摘要 双金属金银纳米粒子（Au-Ag NPs）的合成和生物医学研究因其独特的性质而备受关注。金银纳米粒子的抗菌机制是当前纳米医学工程中的一个热点话题。我们在 Au-Ag NPs 合金的合成中使用了三种途径：i) [HOOC-4-C6H4N N]AuCl4/AgNO3 的共还原，ii) 接种 AuNPs-COOH/AgNO3 和 iii) 将 AgNPs 固定在母体上AuNPs-COOH。使用了两种温和的还原剂 NaBH4 和 9-BBN（9-硼双环（3.3.1）壬烷）。使用透射电子显微镜 (TEM) 和 X 射线光电子能谱 (XPS) 确认了胶体合金纳米粒子结构。使用 NaBH4 还原的颗粒比使用 9-BBN 合成的颗粒大（~20 nm）（