CRISPR recognizes as many phage types as possible without overwhelming the Cas machinery [Biophysics and Computational Biology],Proceedings of the National Academy of Sciences of the United States of America

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CRISPR recognizes as many phage types as possible without overwhelming the Cas machinery [Biophysics and Computational Biology]
Proceedings of the National Academy of Sciences of the United States of America ( IF 11.1 ) Pub Date : 2020-04-07
Michael W. Deem

In 2007, researchers at Danisco interested in fortifying the lactic acid bacteria used to produce dairy products such as milk and cheese against attack by phage showed that CRISPR provided resistance (1). These phage infections were common in industrial dairy fermentation, and it was hugely significant that insertion of multiple...

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