This study aimed to evaluate the effects of kisspeptin-54 immunocastration vaccine on performance, carcass characteristics, meat quality, and safety of Yiling goats. Thirty buck goats were randomly assigned into three groups: PVAX-B2L-Kisspeptin-54-asd immunized (PBK-asd), control, and surgically castrated. PBK-asd immunization significantly stimulated serum anti-kisspeptin antibody production and reduced testosterone hormone compared with the control group (p < .05). Interestingly, PBK-asd plasmid did not integrate into the host genome and had no significant effect on growth hormone, body weight, and average daily gain (ADG). Conversely, surgical castration significantly reduced ADG and carcass weight compared to the control group. Furthermore, PBK-asd immunization did not affect carcass characteristics (dressing percentage, loin area, and fat thickness) and meat quality traits (pH, color, cooking loss, drip loss, and shearing force). These results indicate that the Kisspeptin-54 DNA vaccine is safe and has potential to be used as an alternative to surgical castration for goats without negatively affecting carcass and meat quality.

本研究旨在评估kisepteptin-54免疫cast割疫苗对伊陵山羊的生产性能，car体特性，肉质和安全性的影响。30只雄性山羊随机分为三组：PVAX-B2L-Kisspeptin-54-asd免疫组（PBK-asd），对照组和手术去势组。与对照组（比较PBK-ASD免疫刺激显著血清抗亲吻促动素抗体的产生和减少的睾丸酮激素p <.05）。有趣的是，PBK-asd质粒没有整合到宿主基因组中，并且对生长激素，体重和平均日增重（ADG）没有明显影响。相反，与对照组相比，手术去势显着降低了ADG和car体重量。此外，PBK-asd免疫接种不会影响car体特征（追肥百分率，腰部面积和脂肪厚度）和肉质性状（pH，颜色，蒸煮损失，滴落损失和剪切力）。这些结果表明，Kisspeptin-54 DNA疫苗是安全的，有潜力用作山羊去势手术的替代品，而不会对car体和肉质造成负面影响。