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Both ROSy and Grim: The Landscape of Protein Redox during Aging
Cell Metabolism ( IF 29.0 ) Pub Date : 2020-04-07 , DOI: 10.1016/j.cmet.2020.03.016
Yiwen R. Chen , Daniel F. Jarosz

Covalent cysteine modification by reactive oxygen species (ROS) has been implicated in regulating diverse biological processes, yet global understanding of this modification has remained fragmentary. Developing new approaches for detecting cysteine modification, Xiao et al. (2020) recently charted a comprehensive map of cysteine oxidation across tissues and life stages.



中文翻译:

ROSy和Grim:老化过程中蛋白质氧化还原的态势

活性氧(ROS)对半胱氨酸的共价修饰涉及调节多种生物过程,但是对这种修饰的全球理解仍然是零碎的。Xiao等人开发了检测半胱氨酸修饰的新方法。(2020年)最近绘制了整个组织和生命阶段中半胱氨酸氧化的综合图。

更新日期:2020-04-20
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