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New Microglia on the Block
Cell Metabolism ( IF 29.0 ) Pub Date : 2020-04-07 , DOI: 10.1016/j.cmet.2020.03.015
Eun Sun Jung , Inhee Mook-Jung

Microglia exhibit differing functions and phenotypes depending on life stage and the context of health or disease. Recently, in Nature Neuroscience, Marschallinger et al. (2020) described a new state of microglia, namely “lipid-droplet-accumulating microglia” (LDAM), that contributes to neuronal inflammation and age-related neurodegeneration.



中文翻译:

新小胶质细胞

小胶质细胞表现出不同的功能和表型,具体取决于生命阶段以及健康或疾病的情况。最近,在《自然神经科学》中,Marschallinger等人。(2020)描述了一种新的小胶质细胞状态,即“脂质-液滴累积小胶质细胞”(LDAM),它促进了神经元炎症和与年龄有关的神经变性。

更新日期:2020-04-20
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