Biobased amphiphilic diblock copolymers are prepared thanks to the combination of reversible addition-fragmentation transfer (RAFT) polymerization and polymerization-induced self-assembly (PISA) in an eco-friendly solvent mixture. First, the formation of a poly(acrylic acid) macroRAFT agent (PAA-TTC) is performed in water at 70 °C. Then, in a series of experiments, the PAA-TTC macroRAFT agent is used directly, without purification, as both chain transfer agent and stabilizing agent in the RAFT-PISA of menthyl acrylate (MnA) in dispersion in an ethanol/water mixture. The polymerizations of MnA are fast with high final conversions and well-controlled amphiphilic diblock copolymers are synthesized. Stable, sub-micrometric spherical particles composed of the diblock copolymers are formed. The influence of the monomer concentration and the length of the solvophobic block on the diameter of the self-assemblies is studied by means of dynamic light scattering and cryogenic transmission electron-microscopy.

中文翻译：

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RAFT介导的PISA在绿色溶剂中的生物基两亲嵌段共聚物。

生物基两亲性二嵌段共聚物是通过在生态友好的溶剂混合物中可逆加成-断裂转移（RAFT）聚合和聚合诱导的自组装（PISA）的结合而制备的。首先，在70°C的水中进行聚丙烯酸（丙烯酸）macroRAFT试剂（PAA-TTC）的形成。然后，在一系列实验中，不经纯化直接将PAA-TTC macroRAFT剂直接用作丙烯酸薄荷酯（MnA）在乙醇/水混合物中的RAFT-PISA中的链转移剂和稳定剂。MnA的聚合反应速度快，最终转化率高，可以合成出控制良好的两亲性二嵌段共聚物。形成了由二嵌段共聚物组成的稳定的亚微米球形颗粒。