The infiltration of naïve tissues by myeloid cells has been long related to their clearance and the physiological cell turnover, however, increasing evidence shows that they can additionally fulfill specific, non-immune functions in different tissues. There is also growing evidence to support that infiltrated granulocytes and monocytes respond to different environments by modulating gene expression and cytokine production, which in turn contribute to the normal function of the host tissue. This review will address the roles of immigrated myeloid cells in different tissues and their crosstalk with the host tissue environments.

中文翻译：

---

浸润性粒细胞和单核细胞在体内平衡中的新兴作用。

长期以来，髓样细胞对幼稚组织的浸润与它们的清除率和生理细胞更新有关，然而，越来越多的证据表明，它们可以在不同组织中另外履行特定的非免疫功能。越来越多的证据支持浸润的粒细胞和单核细胞通过调节基因表达和细胞因子产生来响应不同的环境，这反过来又有助于宿主组织的正常功能。这项审查将解决在不同组织中迁移的骨髓细胞的作用及其与宿主组织环境的串扰。