The novel Coronavirus disease 2019 (COVID-19) is caused by SARS-CoV-2, which is the causative agent of a potentially fatal disease that is of great global public health concern. The outbreak of COVID-19 is wreaking havoc worldwide due to inadequate risk assessment regarding the urgency of the situation. The COVID-19 pandemic has entered a dangerous new phase. When compared with SARS and MERS, COVID-19 has spread more rapidly, due to increased globalization and adaptation of the virus in every environment. Slowing the spread of the COVID-19 cases will significantly reduce the strain on the healthcare system of the country by limiting the number of people who are severely sick by COVID-19 and need hospital care. Hence, the recent outburst of COVID-19 highlights an urgent need for therapeutics targeting SARS-CoV-2. Here, we have discussed the structure of virus; varying symptoms among COVID-19, SARS, MERS and common flu; the probable mechanism behind the infection and its immune response. Further, the current treatment options, drugs available, ongoing trials and recent diagnostics for COVID-19 have been discussed. We suggest traditional Indian medicinal plants as possible novel therapeutic approaches, exclusively targeting SARS-CoV-2 and its pathways.

中文翻译：

---

COVID-19：治愈全球恐慌的有希望的方法。

2019 年新型冠状病毒病 (COVID-19) 由 SARS-CoV-2 引起，它是一种潜在致命疾病的病原体，引起了全球公共卫生的极大关注。由于对形势紧迫性的风险评估不充分，COVID-19 的爆发正在全球范围内造成严重破坏。COVID-19 大流行已进入危险的新阶段。与 SARS 和 MERS 相比，由于全球化和病毒在各个环境中的适应能力增强，COVID-19 的传播速度更快。减缓 COVID-19 病例的传播将限制因 COVID-19 病情严重且需要住院治疗的人数，从而显着减轻该国医疗保健系统的压力。因此，最近 COVID-19 的爆发凸显了针对 SARS-CoV-2 的治疗方法的迫切需要。在这里，我们讨论了病毒的结构；COVID-19、SARS、MERS 和普通流感的症状各不相同；感染及其免疫反应背后的可能机制。此外，还讨论了当前针对 COVID-19 的治疗方案、可用药物、正在进行的试验和最新诊断。我们建议印度传统药用植物作为可能的新型治疗方法，专门针对 SARS-CoV-2 及其途径。