Regenerative capacity is robust in the neonatal mouse heart but is lost during postnatal development when cardiomyocytes undergo cell-cycle arrest and polyploidization. In this issue of Developmental Cell, Han et al. (2020) show that Lamin B2, a nuclear lamina filament supporting cardiomyocyte karyokinesis, also facilitates cell division and cardiac regeneration.

中文翻译：

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Lamin B2，心肌细胞核司的守护者。

新生小鼠心脏的再生能力很强，但是当心肌细胞经历细胞周期停滞和多倍体化时，在新生后发育过程中就会丧失。在本期《发育细胞》中，Han等人。（2020年）表明Lamin B2是一种支持心肌细胞核运动的核纤层细丝，也有助于细胞分裂和心脏再生。