Abstract In this methodology, the thiourea (TU) sensor was made-up by means of glassy carbon electrode (GCE) layered by the wet-chemically prepared binary SnO2/V2O5 nanomaterials (NMs). The existence of SnO2 and V2O5 in prepared spherical NPs were categorized by X-ray photoelectron spectroscopy (XPS), Field Emission Scanning Electron Microscopy (FESEM), Energy-dispersive X-ray spectroscopy and X-ray Powder Diffraction (XRD). The TU sensor was displayed the linear responses in concentration range (LDR) of 0.1 nM ~ 0.01 mM. The calibration curve of TU sensor was made by plotting current verses concentration of TU, which was measured by electrochemical technique. The sensitivity and lower limit of detection (DL) for TU sensor were calculated from calibration curve, which are found as 17.0918 µAµM-1cm−2 and 95.40 ± 4.77 pM respectively. The analytical parameters of TU sensor such as reproducibility, response time and stability were measured and found efficient results. It also was validated in the detection of TU in presence of real bio-samples. Thus, this unique and prospective method is introduced to develop the selective biosensor by electrochemical approach, which might be a pioneer sensor probe for its simple and reliable approach for the safety of healthcare and biomedical fields in a large scales.

中文翻译：

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通过电化学方法开发具有二元 SnO2/V2O5 纳米材料的可重现硫脲传感器

摘要 在该方法中，硫脲 (TU) 传感器由玻璃碳电极 (GCE) 组成，该电极由湿化学制备的二元 SnO2/V2O5 纳米材料 (NMs) 分层。通过 X 射线光电子能谱 (XPS)、场发射扫描电子显微镜 (FESEM)、能量色散 X 射线光谱和 X 射线粉末衍射 (XRD) 对制备的球形纳米粒子中 SnO2 和 V2O5 的存在进行分类。TU 传感器在 0.1 nM ~ 0.01 mM 的浓度范围 (LDR) 中显示线性响应。TU 传感器的校准曲线是通过绘制电流与 TU 浓度来绘制的，TU 浓度是通过电化学技术测量的。TU 传感器的灵敏度和检测下限 (DL) 由校准曲线计算，分别为 17.0918 µAµM-1cm-2 和 95.40 ± 4.77 pM。测量了 TU 传感器的分析参数，如重现性、响应时间和稳定性，并发现了有效的结果。它还在存在真实生物样品的情况下检测 TU 中得到验证。因此，引入这种独特且具有前瞻性的方法，通过电化学方法开发选择性生物传感器，因其简单可靠的方法在大规模医疗保健和生物医学领域的安全性方面可能成为先驱传感器探针。