Migration of N,N-Bis(2-hydroxyethyl) alkyl(C8-C18)amines from five different polypropylene capsules to Tenax® and coffee powder have been studied. A single step extraction-cleanup procedure using salting out liquid-liquid extraction (SALLE) method followed by ultra-high performance liquid chromatography-tandem mass spectrometry (UHPLC-MS/MS) was applied. The critical parameters on the SALLE procedure such as extracting solvent, extracting volume, sample pH, salt and its concentration were optimized. The recovery values were in the range of 87.5%-106.5%. The %RSD were lower than 3.7%. The limit of detection was improved from 2.3 ng/g in Tenax® to 0.8 ng/g in coffee. The results indicated that the analyzed compounds have the potential to migrate from the polypropylene capsule containers to the coffee. In most of the cases, the migrated values were higher in Tenax® than in coffee in a range between 1.8 and 61%. One sample did not comply with the specific migration limit established by the European Commission.

中文翻译：

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通过盐辅助液-液萃取和液相色谱-质谱联用，将二羟基烷基胺从聚丙烯咖啡胶囊中迁移到Tenax®和咖啡中。

研究了N，N-双（2-羟乙基）烷基（C8-C18）胺从五个不同的聚丙烯胶囊向Tenax®和咖啡粉的迁移。应用了盐析液-液萃取（SALLE）方法然后超高效液相色谱-串联质谱（UHPLC-MS / MS）的单步萃取-纯化程序。优化了SALLE程序中的关键参数，例如萃取溶剂，萃取体积，样品pH，盐及其浓度。回收率在87.5％-106.5％的范围内。％RSD低于3.7％。检测限从Tenax®中的2.3 ng / g提高到咖啡中的0.8 ng / g。结果表明，所分析的化合物具有从聚丙烯胶囊容器迁移到咖啡中的潜力。在大多数情况下，Tenax®中的迁移值比咖啡中高，介于1.8％和61％之间。一个样本不符合欧盟委员会规定的具体迁移限制。