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LIMD1-AS1 suppressed non-small cell lung cancer progression through stabilizing LIMD1 mRNA via hnRNP U.
Cancer Medicine ( IF 4 ) Pub Date : 2020-04-02 , DOI: 10.1002/cam4.2898
Jianyuan Pan 1 , Yongqin Tang 2 , Shumei Liu 3 , Lily Li 3 , Bo Yu 3 , Yuanyuan Lu 3 , Yu Wang 3
Affiliation  

Non‐small cell lung cancer (NSCLC) occupies the majority of lung cancer cases and is notorious for the awful prognosis. LIM domains‐containing 1 (LIMD1) is suggested as a tumor suppressor in lung cancer, but its mechanism in NSCLC remains elusive. Present study aimed to uncover the mechanism of LIMD1 in NSCLC.

中文翻译:

LIMD1-AS1通过hnRNP U稳定LIMD1 mRNA,从而抑制了非小细胞肺癌的进展。

非小细胞肺癌(NSCLC)占大多数肺癌病例,并且因其可怕的预后而臭名昭著。LIM结构域包含1(LIMD1)被认为是肺癌的肿瘤抑制因子,但其在NSCLC中的作用机制尚不清楚。本研究旨在揭示NSCLC中LIMD1的机制。
更新日期:2020-04-02
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