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Familial hypercholesterolaemia and COVID-19: triggering of increased sustained cardiovascular risk.
Journal of Internal Medicine ( IF 11.1 ) Pub Date : 2020-04-03 , DOI: 10.1111/joim.13070 Alpo Vuorio 1, 2 , Gerald F Watts 3, 4 , Petri T Kovanen 5
Journal of Internal Medicine ( IF 11.1 ) Pub Date : 2020-04-03 , DOI: 10.1111/joim.13070 Alpo Vuorio 1, 2 , Gerald F Watts 3, 4 , Petri T Kovanen 5
Affiliation
Early data from Wuhan, China show that patients with COVID‐19 are typically male, aged 40 to 60 years, and about one‐third have comorbidities. Moreover, of 138 COVID‐19 patients hospitalized in Wuhan and treated in an intensive care unit (ICU), 25% had cardiovascular disease and 58% hypertension; the respective figures for non‐ICU‐treated COVID‐19 patients were 10% and 22% [1]. Based on these early data, a predisposition to acute cardiac complications related to underlying atherosclerotic cardiovascular disease (ASCVD) may significantly increase the severity of COVID‐19 in susceptible individuals.
更新日期：2020-04-03
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