Abstract The new binuclear antimony(III) complexes corresponding to the formulas [SbCl3(µ2-S)(MtMBZIM)2]2 (1), {[SbBr2(µ2-Br)(MtMBZIM)2]2·H2O} (2) and {[SbI2(µ2-I)(MtMBZIM)2]2·H2O} (3) (MtMBZIM: 5-methoxy-2-mercaptobenzimidazole) have been synthesized and structurally characterized with regard to their melting point, elemental analysis, molar conductivity, FT-IR, and FT-Raman spectroscopic techniques, and TG-DTA analysis. The crystal structures of 1-3 have been determined by single-crystal X-ray diffraction. Compounds 1-3 are doubly bridged dimers and in each square pyramidal monomeric unit, the equatorial plane is formed by two sulfur and two halogen atoms in trans-S, trans-X arrangement. The monomeric units in 2 and 3 are linked to each other via halogen bridges, but in 1, they are linked to each other via sulfur bridges; to our knowledge, this binding type is the first example of trans-S, trans-X square pyramidal antimony(III) complexes. Newly synthesized complexes with their corresponding ligand have been tested for their in vitro cytotoxic activity against human adenocarcinoma cervix (HeLa) cells as well as for their antimicrobial activity. The influence of 1-3 on the catalytic peroxidation of the linoleic acid by the enzyme lipoxygenase (LOX) has been determined experimentally and theoretically. Graphical Abstract

中文翻译：

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5-甲氧基-2-巯基苯并咪唑的新型双核锑 (III) 卤化物配合物：合成、结构表征和生物学研究

摘要 对应于式[SbCl3(μ2-S)(MtMBZIM)2]2 (1), {[SbBr2(μ2-Br)(MtMBZIM)2]2·H2O}(2)的新型双核锑(III)配合物和 {[SbI2(µ2-I)(MtMBZIM)2]2·H2O} (3) (MtMBZIM: 5-甲氧基-2-巯基苯并咪唑) 已经合成并在熔点、元素分析、摩尔电导率方面进行了结构表征、FT-IR 和 FT-Raman 光谱技术，以及 TG-DTA 分析。1-3 的晶体结构已通过单晶 X 射线衍射确定。化合物1-3是双桥二聚体，在每个方锥单体单元中，赤道面由两个硫原子和两个卤素原子以反式-S、反式-X排列形成。2和3中的单体单元通过卤素桥相互连接，但在1中，它们通过硫桥相互连​​接；据我们所知，这种结合类型是反式 S、反式 X 方锥体锑 (III) 配合物的第一个例子。新合成的复合物与其相应的配体已被测试其对人腺癌 (HeLa) 细胞的体外细胞毒活性以及抗菌活性。1-3 对通过酶脂肪氧化酶 (LOX) 催化过氧化亚油酸的影响已通过实验和理论确定。图形概要 1-3 对通过酶脂肪氧化酶 (LOX) 催化过氧化亚油酸的影响已通过实验和理论确定。图形概要 1-3 对通过酶脂肪氧化酶 (LOX) 催化过氧化亚油酸的影响已通过实验和理论确定。图形概要