A photocatalytic strategy for regioselective synthesis of phenanthridine derivatives from N-(2-arylbenzylidenamino)pyridinium salts has been developed. Utilization of an Ir photocatalyst, [Ir{dF(CF₃)ppy}₂(dtbbpy)]PF₆ (dF(CF₃)ppy = 3,5-difluoro-2-(5-(trifluoromethyl)-2-pyridyl)phenyl, dtbbpy = 4,4′-di-tert-butyl-2,2′-bipyridine), is a key to successful reactions. The excited Ir catalyst does not serve as a 1e-redox reagent but as an energy donor toward the pyridinium salts. The present system can be also applied to one-pot synthesis of Trisphaeridine, an anti-cancer drug.

中文翻译：

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可见光Ir光催化能量转移驱动的区域选择性合成功能化菲啶

已经开发了从N-（2-芳基亚苄基氨基）吡啶盐区域选择性合成菲啶衍生物的光催化策略。利用Ir光催化剂[Ir {dF（CF ₃）ppy} ₂（dtbbpy）] PF ₆（dF（CF ₃）ppy = 3,5-二氟-2-（5-（三氟甲基）-2-吡啶基） dtbbpy = 4,4'-二叔丁基-2,2'-联吡啶的苯基）是成功进行反应的关键。激发的Ir催化剂不用作1e-氧化还原试剂，而是作为吡啶鎓盐的能量供体。本系统也可以应用于一个一锅法合成Trisphaeridine，一个的抗-cancer药物。