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Coumarin-based fluorescent probe for the rapid detection of peroxynitrite ‘AND’ biological thiols
RSC Advances ( IF 3.9 ) Pub Date : 2020-4-3 , DOI: 10.1039/d0ra02234a
Luling Wu 1 , Xue Tian 1 , Robin R Groleau 1 , Jie Wang 2 , Hai-Hao Han 2 , Shaun B Reeksting 3 , Adam C Sedgwick 4 , Xiao-Peng He 2 , Steven D Bull 1 , Tony D James 1
Affiliation  

A coumarin-based novel ‘AND’ logic fluorescent probe ROS-AHC has been developed for the simultaneous detection of ONOO and biological thiols. ROS-AHC was shown to exhibit only a very small fluorescence response upon addition of a single GSH or ONOO analyte. Exposure to both analytes, however, resulted in a significant fluorescence enhancement.

中文翻译:

用于快速检测过氧亚硝酸盐“AND”生物硫醇的基于香豆素的荧光探针

一种基于香豆素的新型“AND”逻辑荧光探针ROS-AHC已被开发用于同时检测 ONOO -和生物硫醇。ROS-AHC在添加单一 GSH 或 ONOO -分析物时仅表现出非常小的荧光响应。然而,暴露于两种分析物导致显着的荧光增强。
更新日期:2020-04-03
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