The influents and effluents of coastal flow-through aquacultures in Korea were monitored for four selected antibiotics (amoxicillin-AMX, florfenicol-FLO, oxolinic acid-OXO, and oxytetracycline-OTC). A number of 177 samples were obtained from 16 aquaculture facilities for a monitoring period of two years. OTC was detected in 93 samples with a median concentration of 116 ng/L. OXO, FLO, and AMX were also detected in 36, 34, and 22 samples with median concentrations of 90, 44, and 63 ng/L, respectively. After antibiotics were applied to fish tanks, the aquaculture effluents were found to contain antibiotics up to several hundred μg/L, indicating that some control measures are required. Bench-scale experiments showed that chlorine and ozone fully eliminated AMX and OTC but not FLO at ≤2 mg/L of oxidant dosage. Reactive halogen species formed in the marine water matrix enhanced the antibiotic degradation. UV254 most effectively eliminated FLO, achieving 60-70 % elimination at 1000 mJ/cm2 of UV fluence. Sequential use of chlorine followed by UV254 demonstrated significant elimination of all four selected antibiotics. The obtained kinetic information for the reactions of these oxidants and UV with the antibiotics and marine aquaculture water constituents could be useful for designing and optimizing the aquaculture water treatment processes.

中文翻译：

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沿海水产养殖水中的抗生素：氧化水处理过程中的发生和消除效率。

监测了韩国沿海流域水产养殖的进水和出水中四种选定的抗生素（阿莫西林-AMX，氟苯尼考-FLO，草酸-OXO和土霉素-OTC）。在两年的监测期内，从16个水产养殖设施中获得了177个样本。在93个样品中检测到OTC，中值浓度为116 ng / L。还分别在36、34和22个样品中检测到OXO，FLO和AMX，中值浓度分别为90、44和63 ng / L。在鱼缸中使用抗生素后，发现水产养殖废水中的抗生素含量高达几百微克/升，这表明需要采取一些控制措施。基准规模的实验表明，当氧化剂剂量≤2 mg / L时，氯和臭氧可以完全消除AMX和OTC，但不能完全消除FLO。在海水基质中形成的反应性卤素物质增强了抗生素的降解。UV254最有效地消除了FLO，在1000 mJ / cm2的紫外线通量下实现了60-70％的消除。依次使用氯和UV254证明已显着消除了所有四种选定的抗生素。获得的有关这些氧化剂和紫外线与抗生素和海水养殖水成分反应的动力学信息，对于设计和优化养殖水处理工艺可能有用。