Dipleosporalones A and B (1 and 2), two new [2 + 2] azaphilone dimers, were obtained from a marine-derived Pleosporales sp. fungus. The absolute configurations of 1 and 2 were elucidated by calculations of their ECD spectra. Dipleosporalone A (1) possessed an unprecedented skeleton with an uncommon 6/4/6 ring system. Compounds 1 and 2 showed cytotoxicity about 30-90-fold more potent than that of their monomer pinophilin B.

中文翻译：

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Dipleosporalones A和B，来自海洋的Pleosporales sp。的二聚Azaphilones。菌。

Dipleosporalones A和B（1和2），两个新的[2 + 2]氮杂苯甲酮二聚体，是从海洋来源的Pleosporales sp。获得的。菌。1和2的绝对构型通过计算其ECD光谱得以阐明。Dipleosporalone A（1）具有空前的骨架和罕见的6/4/6环系统。化合物1和2的细胞毒性比其单体亲脂蛋白B强约30-90倍。