Stretchable conductive fabric (SCF) is a durable nontoxic textile material coated or blended with conductive metals. Unlike solid metal, SCF effectively conducts electricity with low resistance and maintains conductance when stretched. Thus, we hypothesized that SCF electrodes are more suitable for cardiac electrophysiology applications in beating hearts than traditional solid metal electrodes. Accordingly, we developed a straightforward protocol for fabricating customized SCF electrodes and then assessed their ability to electrically stimulate and record electrical signals from beating hearts. Compared to flexible copper electrodes, SCF electrodes had similar electrical resistance (112.50 ± 25.81 vs 157.85 ± 17.06 Ω, p = 0.09), activated cardiac tissue with lower stimulus strength (27.25 ± 3.52 vs 15.35 ± 2.15 mA, p = 0.0001), recorded stable electrograms with a higher signal-to-noise ratio (20.54 ± 1.09 vs 13.35 ± 1.46 dB, p = 0.04), and were noncorrosive and harmless to cardiac tissue or vasculature. These results support the use of SCF over metal electrodes for a wide range of cardiac electrophysiology applications in the beating heart.

中文翻译：

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用于心脏电生理学应用的可拉伸导电织物

可拉伸导电织物 (SCF) 是一种耐用的无毒纺织材料，涂层或混合有导电金属。与固体金属不同，SCF 以低电阻有效地导电，并在拉伸时保持导电性。因此，我们假设 SCF 电极比传统的固体金属电极更适合心脏跳动中的心脏电生理学应用。因此，我们开发了一种简单的协议来制造定制的 SCF 电极，然后评估它们电刺激和记录跳动心脏电信号的能力。与柔性铜电极相比，SCF 电极具有相似的电阻（112.50 ± 25.81 vs 157.85 ± 17.06 Ω，p= 0.09），激活的心脏组织具有较低的刺激强度（27.25 ± 3.52 vs 15.35 ± 2.15 mA，p = 0.0001），记录的稳定电图具有更高的信噪比（20.54 ± 1.09 vs 13.35 ± 1.46 dB，p = 0.04），并且对心脏组织或脉管系统无腐蚀性和无害。这些结果支持在金属电极上使用 SCF 在跳动的心脏中进行广泛的心脏电生理学应用。