A copper-catalyzed three-component reaction of terminal alkynes, TsN₃, and tertiary allylic amines is developed toward the one-pot synthesis of α-allylic amidines. The product was synthesized on gram scale under 1 mol % of catalyst loading. Transformations of products into alkenyl amine and other nitrogen-containing compounds are demonstrated without any loss of stereochemical information.

中文翻译：

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铜（I）催化的ketenimine形成/氮杂-克莱森重排的立体选择性合成α-烯丙基Al。

铜的末端炔烃，TsN ₃和叔烯丙基胺的三组分反应朝着一锅合成α-烯丙基am的方向发展。在1mol％的催化剂负载下以克规模合成产物。证明了产物向链烯基胺和其他含氮化合物的转化，而没有任何立体化学信息的损失。