The recent guideline on the management of urticaria recommends second‐generation H1 antihistamine as the first‐line therapy, with dose increases of up to fourfold and the addition of omalizumab or cyclosporine if inadequately controlled. However, the treatment of chronic spontaneous urticaria (CSU) is often disappointing. Therefore, a safe and effective treatment option is needed for refractory CSU. To evaluate whether phototherapy can relieve urticarial symptoms and serve as an additional treatment for CSU uncontrolled with antihistamine, we performed a qualitative systematic review. Our result suggests that NBUVB could be an effective complementary treatment modality to manage refractory CSU.

中文翻译：

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光疗可能是可伸缩慢性自发性荨麻疹的有用辅助治疗：系统评价

近期的荨麻疹治疗指南推荐二代 H1 抗组胺药作为一线治疗药物，剂量最多增加 4 倍，如果控制不当，可加用奥马珠单抗或环孢素。然而，慢性自发性荨麻疹 (CSU) 的治疗往往令人失望。因此，难治性 CSU 需要一种安全有效的治疗方案。为了评估光疗是否可以缓解荨麻疹症状并作为抗组胺药无法控制的 CSU 的额外治疗，我们进行了一项定性系统评价。我们的结果表明 NBUVB 可能是治疗难治性 CSU 的有效补充治疗方式。