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Overcoming bottlenecks in plant gene editing.
Current Opinion in Plant Biology ( IF 9.5 ) Pub Date : 2020-03-03 , DOI: 10.1016/j.pbi.2020.01.002
Paul Ap Atkins 1 , Daniel F Voytas 1
Affiliation  

Agriculture has reached a technological inflection point. The development of novel gene editing tools and methods for their delivery to plant cells promises to increase genome malleability and transform plant biology. Whereas gene editing is capable of making a myriad of DNA sequence modifications, its widespread adoption has been hindered by a number of factors, particularly inefficiencies in creating precise DNA sequence modifications and ineffective methods for delivering gene editing reagents to plant cells. Here, we briefly overview the principles of plant genome editing and highlight a subset of the most recent advances that promise to overcome current limitations.

中文翻译:

克服植物基因编辑中的瓶颈。

农业已达到技术拐点。新型基因编辑工具及其向植物细胞递送的方法的开发有望增加基因组的延展性并转化植物生物学。尽管基因编辑能够进行无数的DNA序列修饰,但其广泛采用受到许多因素的阻碍,特别是创建精确的DNA序列修饰效率低下以及将基因编辑试剂传递至植物细胞的方法无效。在这里,我们简要概述了植物基因组编辑的原理,并重点介绍了有望克服当前局限性的最新进展的子集。
更新日期:2020-03-03
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