当前位置: X-MOL 学术BMC Palliat. Care › 论文详情
Our official English website, www.x-mol.net, welcomes your feedback! (Note: you will need to create a separate account there.)
Fatigue, barriers to physical activity and predictors for motivation to exercise in advanced Cancer patients
BMC Palliative Care ( IF 3.1 ) Pub Date : 2020-03-31 , DOI: 10.1186/s12904-020-00542-z
J. Frikkel , M. Götte , M. Beckmann , S. Kasper , J. Hense , M. Teufel , M. Schuler , M. Tewes

In order to counteract fatigue, physical activity (PA) is recommended for all stages of cancer. However, only few advanced cancer patients (ACP) are physically active. Quantitative data with high numbers of ACP reporting barriers to PA are missing. This study aimed to identify barriers to PA in ACP with tiredness/weakness and investigate their motivation towards it. Outpatients with metastatic cancer receiving cancer care at a German Cancer Center reporting moderate/severe tiredness/weakness during self-assessment (MIDOS II) were enrolled. We assessed Fatigue-(FACF-F) and Depression (PHQ8) Scores, demographics, cancer-specific parameters, motivation for PA, physical, psychological and social barriers. 141 of 440 eligible patients (32.0%) with different diagnoses agreed to participate. Patients frequently reported “I feel weakened due to my tumor therapy” (n = 108; 76.6%), physical symptoms (tiredness, weakness, dyspnea, joint-problems, pain, nausea [n = 107; 75.9%]) and fatigue (n = 99; 70.2%) as barriers to PA. However, no significant group differences regarding these barriers were found between physically active and inactive patients. Social barriers were rarely chosen. Motivated patients were 5.6 times more likely to be physically active (p < 0.001), also motivation turned out to be the strongest predictor for a physically active behavior (β = 1.044; p = 0.005). Motivated attitude towards PA was predicted by fatigue (β = − 2.301; p = 0.008), clinically relevant depression (β = − 1.390, p = 0.039), knowledge about PA and quality of life (QoL) (β = 0.929; p = 0.002), PA before diagnosis (β = 0.688; p = 0.005 and Interest in exercise program (β = 0.635; p = 0.008). “I feel weakened due to my tumor therapy” is the most reported barrier to PA among both, physically and inactive patients. Motivation for PA is the strongest predictor of performing PA. Interest in PA, knowledge about PA/QoL and PA before diagnosis are main predictors of a motivated attitude. Absence/presence of social barriers did not associate with motivation, fatigue and depression proved to be a negative predictor. Programs including information, motivational counseling and individualized training should be offered for ACP to overcome barriers and reduce fatigue. German Register of Clinical Trials DRKS00012514, registration date: 30.5.2017.

中文翻译:

疲劳,运动障碍和晚期癌症患者运动动机的预测因子

为了抵抗疲劳,建议对癌症的所有阶段进行体育锻炼(PA)。但是,只有极少数的晚期癌症患者(ACP)具有身体活动能力。缺少大量ACP报告PA障碍的定量数据。这项研究的目的是确定伴有疲劳/虚弱的ACP中PA的障碍,并研究其促成它的动机。在德国癌症中心接受转移性癌症门诊治疗的患者报告了自我评估过程中的中度/重度疲劳/弱点(MIDOS II)。我们评估了疲劳(FACF-F)和抑郁(PHQ8)评分,人口统计学,癌症特定参数,PA动机,身体,心理和社会障碍。440名有不同诊断的合格患者中有141名(32.0%)同意参加。患者经常报告“我因接受肿瘤治疗而感到虚弱”(n = 108; 76.6%),身体症状(疲倦,虚弱,呼吸困难,关节问题,疼痛,恶心[n = 107; 75.9%])和疲劳( n = 99; 70.2%)作为对PA的屏障。但是,在身体活动和不活动的患者之间,没有发现关于这些障碍的显着分组差异。很少选择社会障碍。有动机的患者进行体育锻炼的可能性高5.6倍(p <0.001),而且动机被证明是体育锻炼行为的最强预测因子(β= 1.044; p = 0.005)。通过疲劳(β= − 2.301; p = 0.008),临床相关的抑郁症(β= − 1.390,p = 0.039),对PA的了解和生活质量(QoL)(β= 0.929; p = 0.002),诊断前的PA(β= 0.688; p = 0。005和运动计划兴趣(β= 0.635; p = 0.008)。在身体和不活动的患者中,“我因肿瘤治疗而感到虚弱”是对PA的报道最多的障碍。PA的动机是进行PA的最强预测指标。对PA的兴趣,对PA / QoL的知识以及诊断前对PA的了解是积极态度的主要预测因素。社会障碍的存在与否与动机,疲倦和沮丧无关,被证明是负面的预测因素。应为ACP提供包括信息,动机咨询和个性化培训在内的计划,以克服障碍并减少疲劳。德国临床试验注册证DRKS00012514,注册日期:30.5.2017。身体不活跃的患者。PA的动机是进行PA的最强预测指标。对PA的兴趣,对PA / QoL的知识以及诊断前对PA的了解是积极态度的主要预测因素。社会障碍的存在与否与动机,疲倦和沮丧无关,被证明是负面的预测因素。应为ACP提供包括信息,动机咨询和个性化培训在内的计划,以克服障碍并减少疲劳。德国临床试验注册证DRKS00012514,注册日期:30.5.2017。身体不活跃的患者。PA的动机是进行PA的最强预测指标。对PA的兴趣,对PA / QoL的知识以及诊断前对PA的了解是积极态度的主要预测因素。社会障碍的存在与否与动机,疲倦和沮丧无关,被证明是负面的预测因素。应为ACP提供包括信息,动机咨询和个性化培训在内的计划,以克服障碍并减少疲劳。德国临床试验注册证DRKS00012514,注册日期:30.5.2017。疲劳和沮丧被证明是负面的预测因素。应为ACP提供包括信息,动机咨询和个性化培训在内的计划,以克服障碍并减少疲劳。德国临床试验注册证DRKS00012514,注册日期:30.5.2017。疲劳和沮丧被证明是负面的预测因素。应为ACP提供包括信息,动机咨询和个性化培训在内的计划,以克服障碍并减少疲劳。德国临床试验注册证DRKS00012514,注册日期:30.5.2017。
更新日期:2020-04-22
down
wechat
bug