当前位置: X-MOL 学术J. Heterocycl. Chem. › 论文详情
Our official English website, www.x-mol.net, welcomes your feedback! (Note: you will need to create a separate account there.)
Aqueous‐Mediated green synthesis of novel spiro[indole‐quinazoline] derivatives using kit‐6 mesoporous silica coated Fe3O4 nanoparticles as catalyst
Journal of Heterocyclic Chemistry ( IF 2.4 ) Pub Date : 2020-03-31 , DOI: 10.1002/jhet.3981
Shahrzad Abdolmohammadi 1 , Shahab Shariati 2 , Narges Elmi Fard 3 , Amir Samani 1
Affiliation  

In this work, a series of eight new spiro[3,4′]1,3‐dihydro‐2H ‐indol‐2‐one‐2′‐amino‐4′,6′,7′,8′‐tetrahydro‐2′,5’(1’H ,3’H )‐quinazoline‐diones were successfully synthesized through a three‐component reaction of 1H ‐indole‐2,3‐diones (isatins), guanidine nitrate, and 1,3‐cyclohexanediones, by use of Kit‐6 mesoporous silica coated Fe3O4 nanoparticles (Fe3O4@SiO2@KIT‐6) as a highly efficient magnetically separable nanocatalyst in aqueous media at 60°C. Several notable features of thiseco‐friendly protocol are high yields of products, short reaction times, operational simplicity, and the use of easily available and recyclable catalyst.

中文翻译:

使用试剂盒-6介孔二氧化硅包覆的Fe3O4纳米粒子作为催化剂的新型螺[吲哚-喹唑啉]衍生物的水介导绿色合成

在这项工作中,一系列八个新的螺[3,4'] 1,3-二氢-2 H-吲哚-2-1-2-一氨基-4',6',7',8'-四氢2',5“ - (1” ħ,3' ħ) -喹唑啉二酮通过1的三组分反应成功地合成ħ -吲哚-2,3-二酮(靛红),硝酸胍和1,3-环己烷二酮,使用Kit-6介孔二氧化硅涂覆的Fe 3 O 4纳米颗粒(Fe 3 O 4 @SiO 2@ KIT-6)作为60°C水性介质中的高效磁可分离纳米催化剂。这种环保协议的几个显着特征是产品收率高,反应时间短,操作简便以及使用易于获得且可回收的催化剂。
更新日期:2020-03-31
down
wechat
bug