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Linear Atrophoderma of Moulin.
JAMA Dermatology ( IF 10.9 ) Pub Date : 2020-05-01 , DOI: 10.1001/jamadermatol.2020.0320
Wen-Ming Wang 1 , Yue-Ping Zeng 1
Affiliation  

An adolescent girl presented with a 5-year history of asymptomatic, unilateral brown patches involving the right arm, flank, and leg. She had previously been diagnosed as having morphea and had undergone long-term treatment with glucocorticoids without benefit. There was no other medical or family history of skin disease. Physical examination revealed brown, atrophic patches on the right arm, right side of the trunk, and right leg following Blaschko lines (Figure). There was no associated erythema or sclerotic change. Results of laboratory investigations, including a complete blood cell count and liver and renal function studies, were unremarkable. A lesional skin biopsy specimen was obtained from the right arm, which revealed basket-weave hyperkeratosis, mild atrophy of the spinous layer, hyperpigmentation of the basal layer, and a superficial perivascular infiltrate without thickened collagen bundles in the dermis. Based on the clinical and histopathologic features, a diagnosis of linear atrophoderma of Moulin (LAM) was made.



中文翻译:

线性红木霉菌。

一名青春期女孩,有5年无症状,单侧棕色斑的病史,涉及右臂,胁腹和腿。她先前被诊断出患有吗啡,并接受了糖皮质激素的长期治疗而无济于事。没有其他皮肤病的医学或家族病史。体格检查发现右臂,躯干右侧和右腿遵循Blaschko线呈褐色萎缩斑块(图)。没有相关的红斑或硬化变化。实验室检查的结果,包括完整的血细胞计数和肝肾功能检查,均无异常。从右臂获得病变皮肤活检标本,显示篮子编织过度角化,棘突层轻度萎缩,基底层色素沉着,并渗入浅表血管周,真皮中胶原蛋白束未增厚。根据临床和组织病理学特征,对红磨坊线性萎缩性皮肤病(LAM)进行诊断。

更新日期:2020-05-01
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